Villains from the Marvel comic book universe. Some of these villains are restricted to one series, but because of the nature of the Marvel Universe, many of them appear in multiple comic book titles.
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- Ma Gnucci
- Mad Bomber (videogame)
- Maestro (Marvel)
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- Magneto (X men Movies)
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- Malekith (Thor: The Dark World)
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- Man-Ape (The Avengers: Earth's Mightiest Heroes)
- Mister Sinister
- Mr. Sinister
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- Mysterio (Marvel Cinematic Universe)
- Mystique (X-Men: The Animated Series)
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- Sabretooth (Xmen Movies)
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- Scarecrow (Marvel)
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- Sebastian Shaw
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- Shadow King (Marvel)
- Sigma (Mega Man X)
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- Supreme Intelligence (Marvel Cinematic Universe)
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